The science
Published methods, guideline thresholds, honest limitations.
The panel, cell by cell
One cell per marker CurieSense reads from a standard blood panel — 71 in the sample draw.
Proportion, not identity: cell order is display-only — 23 of 71 markers sat outside their reference range on draw one.
Phenotypic Age (Levine 2018)
PhenoAge is among the best-validated chemistry clocks for mortality risk (Levine et al. 2018); zones follow the InsideTracker/Schneider optimal-zone method.
PhenoAge is computed exactly per Levine et al. 2018 from albumin, creatinine, glucose, CRP, lymphocyte %, MCV, RDW-CV, ALP, WBC, and chronological age. FIB-4, eGFR staging, and the ASCVD proxy use guideline thresholds (AASLD, KDIGO, ACC/AHA) — never invented cutoffs. Single-timepoint clocks overstate when MCV/RDW are extreme, so the report always shows the MCV/RDW-normalized counterfactual alongside.
Sources
- Levine et al. 2018 — an epigenetic biomarker of aging for lifespan and healthspan.
- InsideTracker/Schneider optimal-zone method for reference bands.
CurieSense is an educational research tool, not a medical diagnosis. Always review results with your physician.